Bone turnover markers in patients with type 1 Gaucher disease
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چکیده
منابع مشابه
Bone turnover markers in patients with type 1 Gaucher disease
Bone complications occur frequently in Gaucher disease (GD) and reduce the quality of life of these patients. Skeletal involvement is an important indication for treatment to ameliorate symptoms and reduce the risk of irreversible and debilitating disease. Bone biomarkers have been used to assess disease status and the response to therapy in a number of bone disorders. Here, we examine the lite...
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INTRODUCTION Gaucher cells (GCs), the lipid-laden storage macrophages, are the pathologic hallmark of Gaucher disease (GD). They are typically 20-100 μm in diameter with eccentrically placed nuclei and cytoplasm with characteristic crinkles and striations. A few previous observations have indicated that sometimes GD patients may display morphology of GCs which is different from this classical d...
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This is an uncopyedited electronic version of an article accepted for publication in Diabetes Care. The American Diabetes Association, publisher of Diabetes Care, is not responsible for any errors or omissions in this version of the manuscript or any version derived from it by third parties. The definitive publisherauthenticated version will be available in a future issue of Diabetes Care in pr...
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patients with myeloma is likely to be increased because myeloma-associated with a bleeding diathesis (as the authors note). Indeed, the largest and most recent trial of plasmapheresis for myeloma-associated kidney failure did not specify kidney biopsy as an inclusion criterion because of concerns about the risks vs benefits of the procedure [2]. Can the authors specify how a biopsy result will—...
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Several biochemical markers of bone formation and bone resorption have recently been developed. These markers have been evaluated for clinical utility in patients with metabolic bone disease, including Paget disease and osteoporosis, and for their potential use in cancer patients whose disease has metastasized to bone. We have evaluated seven markers of bone turnover in the plasma and urine of ...
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ژورنال
عنوان ژورنال: Hematology Reports
سال: 2012
ISSN: 2038-8330,2038-8322
DOI: 10.4081/hr.2012.e21